教授
主要涉及吩嗪及吩嗪類衍生物的生物降解功能菌的分離，功能基因的克隆以及代謝途徑的確定。
主要涉及綠針假單胞菌中心代謝途徑的改造以提高莽草酸途徑前體的供給𓀝、莽草酸途徑的強化、吩嗪合成途徑的改造🎼，以高效合成吩嗪類化合物以及其他的新型平臺化合物。
Yao R, Li J, Feng L, Zhang X, Hu H*. 13C metabolic flux analysis-guided metabolic engineering of Escherichia coli for improved acetol production from glycerol. Biotechnol Biofuels, 2019,12:29.
Bilal M, Yue S, Hu H*, Wang W, Zhang X. Adsorption/desorption characteristics, separation and purification of phenazine-1-carboxylic acid from fermentation extract by macroporous adsorbing resins. J. Chem Technol Biotechnol, 2018,93:3176-3184
Yue S, Bilal M, Song C, Guo S,Li S, Huang P, Hu H*, Wang W, Zhang X. Development of an efficient method for separation and purification of trans-2,3-dihydro-3-hydroxyanthranilic acid from Pseudomonas chlororaphis GP72 fermentation broth. Sep Purif Technol. 2018,202,144-148.
Yue S, Bilal M, Guo S, Hu H*, Wang W, Zhang X. Enhanced trans-2,3-dihydro-3-hydroxyanthranilic acid production by pH control and glycerol feeding strategies in engineered Pseudomonas chlororaphis GP72. J. Chem Technol Biotechnol, 2018,93:1618-1626.
Zhao Q, Bilal M,Yue S, Hu H*, Wang W, Zhang X. Identification of biphenyl 2, 3-dioxygenase and its catabolic role for phenazine degradation in Sphingobium yanoikuyae B1. J Environ Manage, 2017, 204: 494-501.
Hu H*, Li Y, Liu K, Zhao J, Wang W, Zhang X. Production of trans-2,3-dihydro-3-hydroxyanthranilic acid by engineered Pseudomonas chlororaphis GP72. Appl Microbiol Biotechnol. 2017, 101: 6607-6613
Zhao Q, Hu H*, Wang W, Huang X,Zhang X. Novel Three-Component Phenazine-1-Carboxylic Acid 1,2-Dioxygenase in Sphingomonas wittichii DP58. Appl Environ Microbiol, 2017,83:e00133
Yao R, Liu Q, Hu H*, Thomas W, Zhang X. Metabolic engineering of Escherichia coli to enhance acetol production from glycerol. Appl Microbiol Biotechnol. 2015, 99: 7945-7952
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