微生物代謝國家重點實驗室學術交流會暨國重實驗室科技創新訓練課程

SKLMM Workshop  （Presentation in English）

報告題目：Complexity Generation in Fungal Natural Product Biosynthesis

報 告  人：Yi Tang  Chancellor Professor

Department of Chemical and Biomolecular Engineering, UCLA

Director, NIH Predoctoral Biotechnology Training Grant

會議時間：9月29日（星期五） 14:00-15:30

會議地點：閔行校區文選醫學大樓1樓報告廳

主 持  人🤴🏻：白林泉 教授

聯 系  人🧙🏻‍♂️：林憶杉 mml@sjtu.edu.cn

報告摘要⚁：

Nature performs challenging synthetic transformations using powerful enzymes.  These enzymes are frequently found in the biosynthetic pathways of natural products, many of which have served as inspirations for generations of synthetic chemists over the last fifty years.  With recent advances in our abilities to manipulate the biosynthetic pathways, many powerful enzymes have been revealed and characterized.  In this talk, I will present a selection of recent work in the identification, characterization and engineering of several enzymes that catalyze difficult transformations and generate structural complexity in fungi.  Examples include multifunctional P450s, Diels Alderases and enzymes that catalyze epoxide rearrangements will be covered.