報告題目：Coordination of virulence traits in Xanthomonas: a common motif with dual role

報 告  人：SUBHADEEP CHATTERJEE教授

Centre for DNA Fingerprinting and Diagnostics

報告時間🤭：10月30日上午9:30-10👨🏻‍🦼：30

報告地點：閔行校區生物醫藥樓3-405

聯 系  人：周蓮 This e-mail address is being protected from spambots. You need JavaScript enabled to view it.

Abstract：

Xanthomonas group of plant pathogens causes diseases in more than 350 different plant hosts. Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xcola) are important members of the genus Xanthomonas which causes serious disease of rice. Xanthomonas coordinates the production of virulence associated function by the production and sensing of fatty acid signaling molecule known as Diffusible signal factor (DSF) by a process known as quorum sensing. We are using molecular genetics and biochemical tools to understand the quorum sensing process in Xoo and Xcola pathogens. Functional studies indicate that Xoo and Xcola regulate the production of virulence associated function in an atypical manner [1, 2]. We have also identified several components of the DSF mediated sensing and factors required for regulation of production of virulence associated functions. We have proposed a model in which DSF regulates functions required for entry, colonization and movement in a contrasting fashion to promote infection and spread inside host. Apart from the role of DSF in quorum sensing, we have identified a novel role of DSF in Xanthomonas-host interaction and signaling which will be discussed.